Lately, the skincare and facial treatment world, especially in Korea, has been buzzing about an active ingredient that’s said to help skin look younger and healthier from within: PDRN Salmon DNA. The term may sound a bit scientific, but its effects in the beauty industry have truly captured widespread attention. It’s particularly popular among those looking to improve skin texture, address signs of aging, and achieve a brighter, more radiant complexion. Here’s an explanation of PDRN skincare and why everyone’s using it right now, the trend that’s currently booming, especially in Korea.
What is PDRN Skincare in Korean Beauty?
PDRN (Polydeoxyribonucleotide) is recognized as a high-value molecule in the medical and beauty fields due to its remarkable ability to regenerate skin tissue. This substance is derived from the sperm cells of salmon or trout, which then undergo an advanced extraction and purification process to achieve a purity level of over 95%.
This process is crucial to ensure that the resulting PDRN is free from contaminants such as proteins, peptides, or lipids that could trigger immunological reactions in the human body. Interestingly, spermatozoa are considered the most ideal DNA source because they possess an exceptionally pure and stable genetic structure.
PDRN molecules work by repairing damaged skin tissue and stimulating the body’s natural collagen production. Collagen, as widely known, is the main protein responsible for skin firmness, elasticity, and suppleness. With increased collagen levels, the skin becomes healthier, more hydrated, and visibly more youthful.
Initially, PDRN was primarily known in the medical field as an active ingredient to support wound healing, tissue regeneration, and post-surgical treatments such as burns or ulcers. However, as dermatological research advanced, the extraordinary benefits of salmon DNA PDRN began to attract the attention of the modern beauty industry. Today, this ingredient has become popular in various skincare products and aesthetic clinic treatments due to its ability to stimulate skin cell repair from within.
Numerous clinical studies have shown that salmon DNA PDRN is safe for use on almost all skin types. This molecule has a high tolerance level, does not cause irritation, and enhances the skin’s natural self-repair abilities. Beyond providing hydration and soothing benefits, PDRN also supports the skin’s natural regeneration process, making it a premium ingredient trusted by many dermatologists to help achieve skin that looks younger, healthier, and more radiant.
PDRN Skincare Benefits
PDRN offers a wide range of skincare benefits. According to Vogue Singapore, Dr. Stephanie Ho, a consultant dermatologist and founder of Stephanie Ho Dermatology, highlights its key advantages:
- Skin Regeneration: Stimulates cell turnover and repairs skin tissue. It means that PDRN treatment can help improve dark circles, especially those caused by thin skin, loss of elasticity, or poor skin regeneration rather than pigmentation alone.
- Anti-Aging: Boosts collagen production, reduces fine lines, and restores skin elasticity.
- Intensive Hydration: Enhances the skin’s ability to retain moisture while strengthening the skin barrier.
- Anti-Inflammatory Effects: Soothes sensitive or irritated skin.
- Wound Healing: Accelerates recovery after laser treatments, microneedling, and acne scars.
- Overall Rejuvenation: Promotes healthier, more radiant-looking skin.
PDRN in Skincare
Source: Pinterest
PDRN, or Polydeoxyribonucleotide as a skincare formula is available in several forms. It can be found in toners, serums, and sheet masks.
1. Topical Products
- PDRN serums and ampoules: Concentrated formulations that deliver PDRN directly to the skin
- PDRN creams and moisturisers: Often combined with other beneficial ingredients for enhanced effects
- Sheet masks: Provide an intensive treatment with prolonged contact
PDRN Skincare Recommendations:
2. Professional Treatments
- PDRN injections: Medical-grade treatments administered by healthcare professionals
- PDRN mesotherapy: Shallow injections into the mesoderm (middle layer of skin)
- Combination therapies: Often paired with microneedling or radiofrequency treatments for enhanced penetration.
How to Incorporate PDRN Skincare Routine
- Patch test: Always test new products on a small area of skin first
- Evening application: Apply PDRN products in the evening when skin cell regeneration is most active
- Simple pairing: Use with gentle, non-active products initially to monitor skin response
- Layer effectively: Apply PDRN serums after cleansing and toning but before heavier creams
- Strategic combinations: Pair with complementary ingredients like peptides, hyaluronic acid, and antioxidants.
Now, you understand what PDRN Salmon DNA is, and why everyone’s using it now, right? With its ability to work deeply down to the cellular level, PDRN is now recognized as one of the best innovations in modern skincare.